The only suggestion I can give is to try different software or a terminal program and connect directly to the machine.
Here are the basics...
Did you install the device driver?
When the laser is connected does it show up in control panels as a CH340 COM port?
Are you selecting the correct COM port and baud rate?
Have you installed and configured the firmware on your machine?
I can walk you through this process with T2Laser but others will need to help with EleksCAM as I've never used it.